Jul 12, 2022

Painting with Yeast Part 1

 

Sir Alexander Fleming was awarded the 1945 Nobel Prize in Physiology or Medicine for his discovery (in the late 1920s) of the antibiotic penicillin. In addition to being an accomplished microbiologist, Dr. Fleming was one of the first to explore microbial art by creating “germ paintings” using living bacteria.

According to Adams and Hendry (2002):

“In microbiology, Alexander Fleming has achieved immortality through his discovery of penicillin but his artistic side is perhaps less well known. He was a lifelong member of the Chelsea Arts Club, a private club for artists of all genres, founded in 1891 at the suggestion of the painter Whistler.


Even in Fleming’s time this technique failed to receive much attention or approval. Apparently he prepared a small exhibit of bacterial art for a royal visit to St Mary’s by Queen Mary. The Queen was not amused and hurried past it even though it included a patriotic rendition of the Union Jack in bacteria.”

*****The colour images were kindly provided by Kevin Brown of the Alexander Fleming Laboratory Museum (Imperial College Healthcare NHS Trust).


Currently the  American Society of Microbiology Agar Art contest run a contest of yeast painting.

The 2017 first-place winner of the American Society for Microbiology Agar Art competition, entitled “Sunset at the End,” by Jasmine Temple, Jef Boeke, PhD, Michael Shen, and Leslie Mitchell, PhD. This piece is composed of Saccharomyces cerevisiae yeast and was printed using nanodroplets of media containing yeast with pigment encoding plasmids on a large agar plate.

***the example above was done with The Echo 650 Liquid Handler is a high-precision lab equipment for scientific research labs



source

yeast art

Dextrose instead of sugar

  The pellicle grew nicely BUT the dextrose measurement * might not be the same as the sugar*  measurement.  Given that the structure is dif...